Just when the Portuguese coach probably assumed his fortune wasn't changing, his side delivered Oliver Glasner's team's initial home loss in league competition from February onward.
The Austrian coach's side had been rampant and deservedly took the lead through the French striker's retaken penalty. However they failed to make their dominance count after previously struggling to score against Palace, the visitors responded two times in quick succession through the Dutch forward plus the former Chelsea player.
The match proved disappointing day concluding following a busy period for the home manager, who witnessed Ismaïla Sarr limp off with a serious problem prior to the break.
Ruben Amorim likely maintained his reactions subdued as he headed down the tunnel immediately after the game's end.
The United manager minimized comparisons between his and Glasner's game philosophy during preparation, while admitting that the opposition "simply perform things better than us|aspects superior to ours|elements more effectively".
The answer to the disappointing loss against 10-man Everton meant modifying both wing-backs, including the young winger shifting to the right side as Diogo Dalot replaced Patrick Dorgu.
Amorim's team probably recognized a chance to benefit considering they enjoyed three more days to prepare and nearly scored first within the first minute.
A lengthy throw-in generated disorder inside Palace's defense yet remarkably the ex-United shot-stopper executed a reflex block near the net to stop the Brazilian.
The close shave acted as an alert for the home team after the early kick-off which was determined for broadcast purposes.
Rapidly attempts commenced appearing in quick succession. Subsequent to squandered multiple opportunities during European action, it seemed like it might not be the Frenchman's match when he twice dragged shots wide of the target in the initial phase.
But in a week when talks over Mateta's contract extension hit obstacles, it was the France international who provided the first goal.
A further accurate delivery by the midfielder drew the defender into the challenge after recently producing superb interception to prevent the Spaniard, the 20-year-old was forced to foul his compatriot within the 18-yard area.
Henderson re-emerged wearing a cap to block the sun from the glare however he'll experience frustration to have allowed United to level the score after the restart.
Palace were caught napping via a fast United dead ball enabling the Dutchman to chest the ball down and swivel in the same movement to unleash an attempt that found the top corner.
Following weathering a frantic moment as the forward came close once more in his own net, their situation enhanced moments after when the Netherlands forward was tripped on the edge of Palace's box from the Palace defender.
There was a moment's hesitation within the barrier when Fernandes rolled the free-kick to Mount permitting Mount to beat Henderson with a powerful drive.
Lacking the winger's speed to utilize, Palace could barely muster additional opportunities while the visitors managed to complete a crucial victory that means Manchester United leapfrog the Eagles up to sixth spot.
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